楼慧强

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中文名
楼慧强
外文名
Lou Huiqiang
国    籍
中国
民    族
汉族
职    业
教授,博士生导师。
性    别

楼慧强教师简介

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2009年中国农业大学特聘教授,同年入选教育部“新世纪优秀人才和创新团队”。
主要以真核微生物酿酒酵母( Saccharomyces cerevisiae )为模式系统,在基因和蛋白相互作用网络水平探求基因组不稳定性的分子机理,及其与疾病/癌症发生的关系。目前致力于相互作用组学技术构建DNA复制期(即S期)的蛋白质调控网络。代表性论文包括Mol Cell封面文章等。

楼慧强学习与工作经历

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2009.3- Professor, Department of Microbiology and Immunology,
College of Biological Sciences, China Agricultural University.
2006.8-2009.3 CIRM Senior Research Fellow,
Divisions of Chemistry and Biology, California Institute of Technology, USA.
2004.8-2006.8 Postdoctoral Scholar,
Division of Chemistry and Chemical Engineering, California Institute of Technology, USA.
1997.9-2004.2 Doctor of Philosophy,
Institute of Microbiology, Chinese Academy of Sciences, China.
1992.9-1997.7 Bachelor of Science,
Department of Cell Biology and Genetics, Peking University, China.

楼慧强研究方向

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In budding yeast:
Genome instability, Diseases and Cancer.
DNA replication and the S phase checkpoint.
DNA damage and replication stress signaling pathways.
Asymmetric segregation and cell aging.
In herperthermophilic archaea:
Genome stability under boiling growth temperature.
Epigenetic adaptation to the extremely harsh environment

楼慧强主讲课程

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研究生课程
《Progress in Microbiology》
《Advanced Progress in Microbiology》
《文献研读》

楼慧强发表文章

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Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C. Reis, Martin Budd, Katsuhiko Shirahige, and Judith L. Campbell*. Mrc1 and DNA polymerase ε function together in linking DNA replication and the S phase checkpoint. Mol. Cell 2008, 32(1):106-117. (On the cover).
[Previews] Labib Karim, Making Connections at DNA Replication Forks: Mrc1 Takes the Lead. Mol. Cell, 2008, 32(2):166-168.
Huiqiang Lou, Zhenhong Duan, Tong Sun, and Li Huang*. Cleavage of double-stranded DNA by the intrinsic 3’-5’ exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. FEMS Microbiol. Lett. 2004, 231: 111-117.
Huiqiang Lou, Zhenhong Duan, Xiaofeng Huo, and Li Huang*. Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins. J Biol. Chem. 2004, 279(1):127-32.
Likui Zhang, Huiqiang Lou, et. al. Extremophile. Published online: 11 December 2009
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参考资料
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